Epic has rocked the video game industry by laying off 16% of its workforce, nearly 900 people. While layoffs and studio closures and game cancellations are all too common in the industry, this was worse than usual, given the context in which they took place.
Digital Extremes also did, since UT'99 I believe. And they are still okay. Their current f2p game feels better than UT3 ever did, if not for it's own problems.