https://en.wikipedia.org/wiki/Hyperoxia
This was a screenshot I took months ago while watching a Geology Hub upload on YT. It was a lightbulb moment for my understanding of mass extinction events, (the largest was 250ma). I’ve referenced this multiple times, so thought I might share. Perhaps you find it as interesting as I do.
There are 850k people living in La Paz, Bolivia (elevation 3650m) with the equivalent of 13.2% sea level oxygen and they seem to be doing just fine. And granted, the natives of the region display some hemoglobin adaptation, but still… Even Aspen, Colorado sits at about 15% sea level oxygen and I’m pretty sure people don’t wear breathing gear while skiing there.